Ausgewählte Forschungsgebiete:

• (Neuro-)Toxizität von Lebensmittelkontaminanten
• Auswirkungen einer zellulären Kupfer Dyshomöostase
• Interaktionen von Spurenelementen
• Bioimaging

Neueste Publikationen 

• M. Tuchtenhagen, M. Stiboller, B. Witt, T. Schwerdtle:
  A novel approach for the determination of exchangeable copper in serum using protein precipitation.
  J Anal At Spectrom, 38, 587-594, 2023. DOI: 10.1039/D2JA00355D
• M. M. Nicolai, B. Witt, S. Friese, V. Michaelis, L. Holz-Armstrong, M. Martin, F. Ebert, T. Schwerdtle, J. Bornhorst:
  Mechanistic studies on the adverse effects of manganese overexposure in differentiated LUHMES cells
  Food Chem Toxicol, 161:112822, 2022. DOI: 10.1016/j.fct.2022.112822.
• M. M. Nicolai, B. Witt, A. Hartwig, T. Schwerdtle, J. Bornhorst:
  A fast and reliable method for monitoring genomic instability in the model organism Caenorhabditis elegans.
  Arch Toxicol, 95(10):3417-3424, 2021. DOI: 10.1007/s00204-021-03144-7
• V. K. Wandt, N. Winkelbeiner, J. Bornhorst, B. Witt, S. Raschke, L. Simon, F. Ebert, A. P. Kipp, T. Schwerdtle:
  A matter of concern – trace element dyshomeostasis and genomic stability in neurons.
  Redox Biology, 41:101877, 2021. DOI: 10.1016/j.redox.2021.101877
• B. Witt, M. Stiboller, S. Raschke, S. Friese, F. Ebert, T. Schwerdtle:
  Characterizing effects of excess copper levels in a human astrocytic cell line with focus on oxidative stress markers.
  J Trace Elem Med Biol, 65:126711, 2021. DOI: 10.1016/j.jtemb.2021.126711
• B. Witt, D. Schaumlöffel, T. Schwerdtle:
  Subcellular Localization of Copper—Cellular Bioimaging with Focus on Neurological Disorders.
  Int J Mol Sci, 21:2341, 2020. DOI: 10.3390/ijms21072341
• F. Ebert, V. Ziemann, V. K. Wandt, B. Witt, S. M. Müller, N. Guttenberger, E. E. Bankoglu, H. Stopper, G. Raber, K. A. Francesconi, T. Schwerdte, Tanja:
  Cellular toxicological characterization of a thioxolated arsenic-containing hydrocarbon.
  J Trace Elem Med Biol, 61:126563, 2020. DOI: 10.1016/j.jtemb.2020.126563
• B. Witt, F. Ebert, S. Meyer, K. A. Francesconi, T. Schwerdtle:
  Assessing neurodevelopmental effects of arsenolipids in pre-differentiated human neurons.
  Mol Nutr Food Res, 61(11), 2017. DOI: 10.1002/mnfr.201700199
• B. Witt, J. Bornhorst, H. Mitze, F. Ebert, S. Meyer, K. A. Francesconi, T. Schwerdtle:
  Arsenolipids exert less toxicity in a human neuron astrocyte co-culture as compared to the respective monocultures.
  Metallomics, 9(5):442-446, 2017. DOI: 10.1039/c7mt00036g
• B. Witt, S. Meyer, F. Ebert, K. A. Francesconi, T. Schwerdtle:
  Toxicity of two classes of arsenolipids and their water-soluble metabolites in human differentiated neurons.
  Arch Toxicol, 91(9):3121-3134, 2017. DOI: 10.1007/s00204-017-1933-x
• FF. Ebert, M. Thomann, B. Witt, S. M. Müller, S. Meyer, T. Weber, M. Christmann, T. Schwerdtle: Evaluating long-term cellular effects of the arsenic species thio-DMA^V: qPCR-based gene expression as screening tool.
  J Trace Elem Med Biol, 37:78-84, 2016.DOI: 10.1016/j.jtemb.2016.06.004
• A. Semisch, J. Ohle, B. Witt, A. Hartwig:
  Cytotoxicity and genotoxicity of nano- and microparticulate copper oxide: role of solubility and intracellular bioavailability.
  Part Fibre Toxicol, 11(1):10, 2014. DOI: 10.1186/1743-8977-11-10
• D. W. Lachenmeier, R. Godelmann, B. Witt, K. Riedel, J. Rehm:
  Can resveratrol in wine protect against the carcinogenicity of ethanol? A probabilistic dose-response assessment.
  Int J Cancer, 134 (1):144-53, 2014. DOI: 10.1002/ijc.28336