Lecturer: M. Deponte

Course: See here

Term: Summer semester

Venue & Time:

HS 52-207 / Mon 8⁴⁵ - 9³⁰ 

HS 52-204 / Tue 10¹⁵ - 11⁴⁵

Content:

• Advanced amino acid metabolism (rep. amino acids, enzyme mechanisms, connections with carbon metabolism, mediators/hormons/neurotransmitters, nitrogen excretion)
• Protein structure (rep. primary to quaternary structure, folding problem, structure-function relationships)
• Intracellular protein turnover (synthesis, folding, sorting, secondary modifications, degradation)
• Protein production and purification (methods in research & industry)

OpenOlat Material: See here

Lecturer: M. Deponte

Course: See here

Term: Summer semester

Venue & Time:

Room 54-582 / flexible

Content:

• Overview and phylogeny of parasitic protists
• Special cell organelles and metabolic pathways
• Molecular parasitology
• Chemical and genetic rescue strategies
• Drug development (screening vs. rational drug design, target identification)
• Resistance mechanisms
• Current parasite/pathway/drug study of choice

OpenOlat Material: See here

Lecturer: M. Deponte

Course: See here

Term: Winter semester

Venue & Time:

HS 52-204 / Mon 12¹⁵ - 13⁴⁵ 

HS 46-280 / Wed 8⁴⁵ - 9³⁰

Content:

• Introduction (organismic diversity, metabolic compartmentalization)
• Comparison of metabolic pathways (examples of analogous & differing reactions, purine and pyrimidine metabolism)
• Model systems and applications (eukaryotic and prokaryotic model systems, molecular tools)
• Comparison of pro- and eukaryotes (energy metabolism, information systems, growth and reproduction, optional: defence & immune systems or motility)

OpenOlat Material: See here

Lecturer: M. Deponte

Course: See here

Term: Winter semester

Venue & Time:

Room 54-582 / Tue 9⁰⁰ - 10⁴⁵ 

Content:

• Enzyme classification
• Principles of enzyme catalysis
• Steady-state and pre-steady state kinetics
• Enzyme inhibitors
• Allostery and cooperativity
• Data analysis and evaluation
• Selected enzyme mechanisms and examples

OpenOlat Material: See here

Supervisor: M. Deponte

Course: See here

Term: WiSe/SuSe

Content:

Selected current biochemical research in enzymology and/or molecular parasitology, e.g., methods in molecular biology, cell culture, CRISPR-Cas9 genetics, western blot analysis, protein purification, steady-state and/or stopped-flow enzyme kinetic measurements. The exact content of the practical module depends on current research activities. 

Supervision capacity and internship options are limited. Please plan ahead and submit a timely request via email.

Supervisor: M. Deponte

Course: See here

Term: WiSe/SuSe

Content:

Selected current biochemical research methods in enzymology and protein structure-function analyses. The exact content of the practical module depends on current research activities. 

Supervision capacity and internship options are limited. Please plan ahead and submit a timely request via email.