Arbeitsgruppe Esselen

Publikationen

  • Solecki, G.M., Kajzar, J., Haushofer, C., Scherhag, A., Schrenk, D., Esselen, M. (2013) Genotoxic Properties of Cyclopentenone Prostaglandins and the Onset of Glutathione Depletion. Chem. Res. Toxicol, 18; 252-61.
  • Esselen, M., Winkler, S., Baechler, S., Barth, SW., Briviba, K., Watzl, B., Skrbek, S., Marko, D. (2013) Anthocyanins suppress the cleavable complex formation by irinotecan and diminish its DNA strand breaking activity in the colon of Wistar rats, Carcinogensis, 34, 835-40.
  • Groh, I.A.M., Chen, C., Lüske, C., Cartus, AT., Esselen, M. (2013) Plant Polyphenols and Oxidative Metabolites of the Herbal Alkenylbenzene Methyleugenol Suppress Histone Deacetylase Activity in Human Colon Carcinoma Cells, Journal of Nutrition and Metabolism, doi:10.1155/2012/821082.
  • Teller, N, Roth M, Esselen, M, Fridrich, D, Boettler, U., Blust, V., Will, F., Dietrich, H., Raule, F., Hümmer, W., Richling, E., Schreier, P., Marko, D. (2013) Apple procyanidins affect several members of the ErbB receptor tyrosine kinase family, Food Funct., 2013 Feb 13. [Epub ahead of print].
  • Groh, I.A.M., Cartus, A. T., Vallicotti, S., Kajzar, J., Merz, K. H., Schrenk, D., Esselen, M (2012) Genotoxic potential of methyleugenol and selected methyleugenol metabolites in cultured Chinese hamster V79 cells. Food Funct., 3, 428-436.
  • Gehrke, H., Frühmesser, A., Pelka, J., Esselen, M., Hecht, L. L., Blank, H., Schuchmann, H. P., Gerthsen, D., Marquardt, C., Diabaté, S., Weiss, C., Marko, D. (2012) In vitro toxicity of amorphous silica nanoparticles in human colon carcinoma cells. Nanotoxicology. Jan 20. [Epub ahead of print]
  • Esselen, M., Boettler, U., Teller, N., Bachler, S., Hutter, M., Rufer, C. E., Skrbek, S., Marko, D. Anthocyanin-rich blackberry extract suppresses the DNA-damaging properties of topoisomerase I and II poisons in colon carcinoma cells. J Agric Food Chem. 2011, 59, 6966-73.
  • Esselen, M., Fritz, J., Hutter, M., Teller, N., Baechler, S., Boettler, U., Marczylo, T.H., Gescher, A.J., Marko, D. (2011) Anthocyanin-rich extracts suppress the DNA-damaging effects of topoisomerase poisons in human colon cancer cells. Mol Nutr Food Res. 55, 143-53.
  • Barth, S. W., Briviba, K., Watzl, B., Jäger, N., Marko, D. (2010) Esselen, M. In vivo bioassay to detect irinotecan-stabilized DNA-topoisomerase I complexes in rats. Biotechnology Journal 5, 321-7.
  • Esselen, M., Fritz, J., Hutter, M., Marko, D. (2009) Delphinidin modulates the DNA-damaging properties of topoisomerase II poisons. Chem Res Toxicol. 22, 554 – 564.
  • Skrbek, S., Rüfer, C. E., Marko, D., Esselen, M. (2009) Quercetin and its microbial degradation product 3,4-dihydroxphenylacetic acid generate hydrogen peroxide modulating their stability under in vitro conditions. JFNR 3, 129 – 140.
  • Pelka, J., Gehrke, H., Esselen, M., Türk, M., Crone, M., Bräse, S., Muller, T., Blank, H., Send, W., Zibat, V., Brenner, P., Schneider, R., Gerthsen, D., Marko, D. (2009) Cellular uptake of platinum nanoparticles in human colon carcinoma cells and their impact on cellular redox systems and DNA integrity. Chem Res Toxicol. 22, 649-59.
  • Fridrich, D., Glabasnia, A., Fritz, J., Esselen, M., Pahlke, G., Hofmann, T., Marko, D. (2008) Oak ellagitannins suppress the phosphorylation of the epidermal growth factor receptor in human colon carcinoma cells. J Agric Food Chem. 56, 3010-5.
  • Fridrich, D., Teller, N., Esselen, M., Pahlke, G., Marko, D. (2008) Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation. Mol Nutr Food Res. 52, 815-22.
  • Fritz, J., Roth, M., Holbach, P., Esselen, M., Marko, D. (2008) Impact of delphinidin on the maintenance of DNA integrity in human colon carcinoma cells. J Agric Food Chem. 56, 8891-6.
  • Fridrich D, Kern M, Fritz J, Pahlke G, Kohler N, Winterhalter P, Marko D. (2007) The epidermal growth factor receptor and human topoisomerases represent potential cellular targets of oligomeric procyanidins. Mol Nutr Food Res. 51, 192-200.
  • Fridrich D, Kern M, Pahlke G, Volz N, Will F, Dietrich H, Marko D. (2007) Apple polyphenols diminish the phosphorylation of the epidermal growth factor receptor in HT29 colon carcinoma cells. Mol Nutr Food Res. 51, 594-601.
  • Kern M, Pahlke G, Balavenkatraman KK, Böhmer FD, Marko D. (2007) Apple polyphenols affect protein kinase C activity and the onset of apoptosis in human colon carcinoma cells. J. Agric. Food Chem. 55, 4999-5006.
  • Kern M, Fridrich D., Reichert J., Skrbek S., Nussher A., Hofem S., Vatter S., Pahlke P., Rüfer C. E, Marko D. (2007) Limited stability in cell culture medium and hydrogen peroxide formation affect the growth inhibitory properties of delphinidin and its degradation product gallic acid. Mol Nutr Food Res. 51, 1163-72.
  • Fritz, J., Kern, M., Pahlke, G., Vatter, S. and Marko, D. (2006) Biological activities of malvidin, a red wine anthocyanidin Mol Nutr Food Res, 50, 390-395
  • Kern, M., Pahlke, P., Ngiewih, Y. and Marko, D. (2006) Modulation of key elements of the Wnt pathway by apple polyphenols. J. Agric. Food Chem. 54, 7041-7046.
  • Pahlke, P., Ngiewih, Y., Kern, M., Jakobs, S., Marko, D. and Eisenbrand, G. (2006) Impact of quercetin and EGCG on key elements of the Wnt pathway in human colon carcinoma cells. J. Agric. Food Chem. 54, 7075-7082.
  • Kern, M.; Tjaden, Z.; Ngiewih, Y.; Puppel, N.; Will, F.; Dietrich, H.; Pahlke, G.; Marko, D. (2005) Inhibitors of the epidermal growth factor receptor in apple juice extract. Mol Nutr Food Res, Apr; 49(4):317-28.

 

 

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